The Tyrosine Aminomutase TAM1 Is Required for β-Tyrosine Biosynthesis in Rice
نویسندگان
چکیده
منابع مشابه
A novel 4-methylideneimidazole-5-one-containing tyrosine aminomutase in enediyne antitumor antibiotic C-1027 biosynthesis.
The C-1027 enediyne antibiotic contains an unusual 3-chloro-4,5-dihydroxy-beta-phenylalanine moiety that is thought to be derived from tyrosine by an aminomutase reaction. However, none of the genes identified within the C-1027 gene cluster encode proteins with strong homology to known aminomutases. The sgcC4 gene encodes a protein with strong homology to dehydroalanine-dependent histidine/phen...
متن کاملTyrosine dephosphorylation is required for Bak activation in apoptosis.
Activation of the cell-death mediator Bak commits a cell to mitochondrial apoptosis. The initial steps that govern Bak activation are poorly understood. To further clarify these pivotal events, we have investigated whether post-translational modifications of Bak impinge on its activation potential. In this study, we report that on apoptotic stimulation Bak undergoes dephosphorylation at tyrosin...
متن کاملEngineering of an enantioselective tyrosine aminomutase by mutation of a single active site residue in phenylalanine aminomutase.
By replacing a single active-site residue Cys107 with Ser in phenylalanine aminomutase (PAM), the enzyme gained tyrosine aminomutase (TAM) activity while retaining PAM activity and high enantioselectivity. This engineered enantioselective TAM also catalyzed formation of β-tyrosine from p-coumaric acid and may prove to be useful for the synthesis of enantiopure β-tyrosine and its derivatives.
متن کاملPhenylalanine-Tyrosine Biosynthesis in NEUROSPORA CRASSA.
IOCHEMICAL investigations of the phenylalanine-tyrosine specific portion of the aromatic pathmway reveal a reaction sequence depicted in Figure 1. Although the organisms studied use similar intermediates to accomplish phenylalanine and tyrosine synthesis, some important functional differences exist. Aerobacter aerogenes and Escherichia coli W possess two molecular forms of chorismate mutase sep...
متن کاملJunctional protein MAGI - 3 interacts with receptor tyrosine phosphatase β ( RPTP β ) and tyrosine - phosphorylated proteins
Receptor protein tyrosine phosphatase β (RPTPβ, also known as RPTPζ) and RPTPγ are members of a distinct group of phosphatases, characterized by the presence of carbonic-anhydrase-like (CAH) and fibronectin type III (FNIII) domains in their extracellular region (Barnea et al. In common with other receptor protein tyrosine phosphatases, RPTPβ mediates cell-cell and cell-matrix interactions and i...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Plant Cell
سال: 2015
ISSN: 1040-4651,1532-298X
DOI: 10.1105/tpc.15.00058